Best Acne Spot Treatment in 2025

Rank by price Audience favorites FAQ
Total products
14
Price range
$6 - $45
Products tested
29

Acne spot treatments help to clear stubborn breakouts quickly. Learn about the best options that target blemishes, reduce redness and inflammation, and prevent future flare-ups.

Product Reviews

1
Mario Badescu Drying Lotion

Mario Badescu Drying Lotion

Aproximate Price Mario Badescu Drying Lotion: $17

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2
Clean & Clear Advantage Spot Treatment

Clean & Clear Advantage Spot Treatment

Aproximate Price Clean & Clear Advantage Spot Treatment: $7

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3
Origins Super Spot Remover Acne Treatment Gel

Origins Super Spot Remover Acne Treatment Gel

Aproximate Price Origins Super Spot Remover Acne Treatment Gel: $20

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4
The Ordinary Salicylic Acid 2% Solution

The Ordinary Salicylic Acid 2% Solution

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5
COSRX Acne Pimple Master Patch

COSRX Acne Pimple Master Patch

Aproximate Price COSRX Acne Pimple Master Patch: $6

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6
TruSkin Tea Tree Oil Super Serum For Face

TruSkin Tea Tree Oil Super Serum For Face

Aproximate Price TruSkin Tea Tree Oil Super Serum For Face: $25

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7
Kate Somerville EradiKate Acne Treatment

Kate Somerville EradiKate Acne Treatment

Aproximate Price Kate Somerville EradiKate Acne Treatment: $28

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8
Tula Go Away Acne Spot Treatment

Tula Go Away Acne Spot Treatment

Aproximate Price Tula Go Away Acne Spot Treatment: $22

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9
Murad Deep Relief Acne Treatment with 2% Salicylic Acid

Murad Deep Relief Acne Treatment with 2% Salicylic Acid

Aproximate Price Murad Deep Relief Acne Treatment with 2% Salicylic Acid: $45

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10
Hero Cosmetics Mighty Patch Invisible+

Hero Cosmetics Mighty Patch Invisible+

Aproximate Price Hero Cosmetics Mighty Patch Invisible+: $18

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11
Renée Rouleau Night Time Spot Lotion

Renée Rouleau Night Time Spot Lotion

Aproximate Price Renée Rouleau Night Time Spot Lotion: $34

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12
White Willow Sleep Mask & Spot Treatment

White Willow Sleep Mask & Spot Treatment

Aproximate Price White Willow Sleep Mask & Spot Treatment: $45

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13
Neutrogena On-the-Spot Acne Treatment

Neutrogena On-the-Spot Acne Treatment

Aproximate Price Neutrogena On-the-Spot Acne Treatment: $10

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14
Solawave Bye Acne: 3-Minute Pimple Spot Treatment

Solawave Bye Acne: 3-Minute Pimple Spot Treatment

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Recap of Best Acne Spot Treatment

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