Best Drugstore Serum in 2025

Total products
13
Price range
$9 - $40
Products tested
37

High-quality skincare doesn't always need to break the bank. This review focuses on the best drugstore serums that offer maximum benefits at a budget price. These serums target specific skin concerns such as aging, dryness, and hyperpigmentation, while also providing overall skin health improvement.

Product Reviews

1
Vichy Mineral 89 Hyaluronic Acid Serum

Vichy Mineral 89 Hyaluronic Acid Serum

Aproximate Price Vichy Mineral 89 Hyaluronic Acid Serum: $20

If you're on the hunt for a game-changing serum that won't break the bank, then look no further. This gem packs a punch with its minimalist formula boasting natural origin hyaluronic acid alongside 89% Vichy volcanic water, providing a hydration boost that really plumps up the skin. It's like a tall glass of water for your face, leaving it looking refreshed and radiant. Lightweight and fast-absorbing, it lays down a perfect canvas for makeup or works as a standalone hero for those no-fuss days. You don't need to empty your wallet on high-end serums when this affordable bottle delivers visible results and strengthens the skin barrier. It's definitely a top contender for best drugstore serum, earning its rightful place in anyone's daily skincare regime.

Where to buy Vichy Mineral 89 Hyaluronic Acid Serum :

2
The Ordinary Hyaluronic Acid 2% + B5

The Ordinary Hyaluronic Acid 2% + B5

Aproximate Price The Ordinary Hyaluronic Acid 2% + B5: $9

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3
Neutrogena Hydro Boost Hydrating Serum

Neutrogena Hydro Boost Hydrating Serum

Aproximate Price Neutrogena Hydro Boost Hydrating Serum: $31

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Where to buy Neutrogena Hydro Boost Hydrating Serum :

4
Versed Just Breathe Clarifying Serum

Versed Just Breathe Clarifying Serum

Aproximate Price Versed Just Breathe Clarifying Serum: $20

This serum is a total game-changer if you're looking for high-quality skincare without breaking the bank. It effortlessly earns its spot on the best drugstore serum list because it's packed with powerhouse ingredients like niacinamide and salicylic acid that work overtime to calm inflammation and keep breakouts at bay. I absolutely love how lightweight and absorbent it is—no greasy residue, just smooth, clarified skin. It's like a deep breath for your face, soothing and refreshing, and honestly, for the price, it's a total steal. If you're battling oily or acne-prone skin, this is the budget-friendly miracle you've been waiting for.

Where to buy Versed Just Breathe Clarifying Serum :

5
Acure Brightening Glowing Serum

Acure Brightening Glowing Serum

Aproximate Price Acure Brightening Glowing Serum: $16

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6
Differin Dark Spot Correcting Serum

Differin Dark Spot Correcting Serum

Aproximate Price Differin Dark Spot Correcting Serum: $30

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7
Olay Regenerist Regenerating Serum

Olay Regenerist Regenerating Serum

Aproximate Price Olay Regenerist Regenerating Serum: $37

This serum is a hidden gem among the shelves of the drugstore, offering a luxurious experience without the hefty price tag. Its lightweight formula is silky smooth, gliding onto your skin as if you're pampering yourself at a high-end spa. Packed with skin-loving ingredients like amino-peptides, niacinamide, and hyaluronic acid, it works tirelessly to regenerate and rejuvenate your complexion, leaving it feeling supple and looking youthful. With consistent use, you'll notice a marked improvement in the texture and firmness of your skin. It's a fantastic choice for anyone looking to step up their skincare game without breaking the bank. Whether you have dry, oily, or combination skin, this serum adapts to your needs and delivers results that will make you question why you ever considered splurging on more expensive alternatives.

Where to buy Olay Regenerist Regenerating Serum :

8
The Ordinary Lactic Acid 10% + HA

The Ordinary Lactic Acid 10% + HA

Aproximate Price The Ordinary Lactic Acid 10% + HA: $9

If you're on the hunt for an affordable powerhouse serum that can smooth skin texture and promote a radiant complexion, look no farther than this gem from the drugstore aisles. Blitzing away dead skin cells with 10% lactic acid, it's a gentle yet effective exfoliant for those not quite ready to dive into the more intense world of glycolic acid. Plus, with the added benefit of hyaluronic acid, it hydrates your skin, leaving it plump and dewy rather than stripped and dry. No frills, no fancy packaging, just results that rival those of its high-end counterparts. A real stand-out in the saturated skincare market, it's a must-try for any savvy beauty shopper looking to get the most bang for their buck.

Where to buy The Ordinary Lactic Acid 10% + HA :

9
Vichy LiftActiv Vitamin C Brightening Face Serum

Vichy LiftActiv Vitamin C Brightening Face Serum

Aproximate Price Vichy LiftActiv Vitamin C Brightening Face Serum: $35

This serum is a game-charger for anyone seeking a radiant glow without breaking the bank. Its potent blend of 15% pure vitamin C and hyaluronic acid works wonders, visibly brightening and firming the skin within just a few weeks of regular use. It's refreshingly lightweight and absorbs quickly, making it a hassle-free addition to any skincare routine. Even better, it's suitable for sensitive skin and doesn't leave behind any sticky residue. For a drugstore option, it punches way above its weight, giving some of the pricier brands a run for their money. If you're looking to add some serious luminosity to your complexion without emptying your wallet, this serum is definitely worth the try.

Where to buy Vichy LiftActiv Vitamin C Brightening Face Serum :

10
L'Oréal Paris Revitalift 1.5% Pure Hyaluronic Acid Serum

L'Oréal Paris Revitalift 1.5% Pure Hyaluronic Acid Serum

Aproximate Price L'Oréal Paris Revitalift 1.5% Pure Hyaluronic Acid Serum: $33

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11
RoC Retinol Correxion Smoothing Night Serum Capsules

RoC Retinol Correxion Smoothing Night Serum Capsules

Aproximate Price RoC Retinol Correxion Smoothing Night Serum Capsules: $33

These little capsules are a game-changer for seamless, affordable skincare right from your drugstore aisle. Packed with potent retinol, they tackle fine lines and wrinkles head-on, delivering smoother, more youthful-looking skin without breaking the bank. The single-use design ensures each dose is fresh and precisely measured, eliminating any guesswork and making them incredibly convenient for travel. Perfect for anyone dipping their toes into the retinol pool, they boast a gentler formula that doesn't skimp on efficacy. An overnight sensation, they work their magic while you sleep, so you wake up to visibly rejuvenated skin. Truly, these capsules stand out as a top-tier drugstore serum, offering luxury results without the luxury price tag.

Where to buy RoC Retinol Correxion Smoothing Night Serum Capsules :

12
La Roche-Posay 10% Pure Niacinamide Face Serum

La Roche-Posay 10% Pure Niacinamide Face Serum

Aproximate Price La Roche-Posay 10% Pure Niacinamide Face Serum: $40

This serum is a game changer for anyone on the hunt for top-tier skincare without the hefty price tag. Boasting a potent 10% concentration of Niacinamide, it's a powerhouse for tackling all sorts of skin woes from redness and blemishes to uneven tone and texture. The lightweight formula sinks right into the skin, leaving no sticky residue, just a smooth, matte finish that's perfect even under makeup. Plus, with the trusted La Roche-Posay name behind it, you know you're getting quality that often rivals luxury brands. For the price, efficacy, and accessibility, it truly stands out as a drugstore gem that gives your skin that coveted healthy glow without breaking the bank.

Where to buy La Roche-Posay 10% Pure Niacinamide Face Serum :

13
CeraVe Resurfacing Retinol Serum

CeraVe Resurfacing Retinol Serum

Aproximate Price CeraVe Resurfacing Retinol Serum: $22

This serum is a game-changer for anyone looking for powerhouse results without breaking the bank. It's a standout in the drugstore aisle, blending affordability with the effectiveness of retinol to tackle pesky skin issues like post-acne marks and uneven texture. Lightweight and surprisingly gentle on the skin, it doesn't just superficially smooth; it goes deep to resurface your complexion, leaving you with a noticeable glow. Plus, it's formulated with ceramides, which help maintain your skin's natural barrier, so you get all the benefits of retinol without harsh irritation. No wonder it's a crowd favorite – it delivers results that you'd expect from high-end serívces, but at a fraction of the price.

Where to buy CeraVe Resurfacing Retinol Serum :

Recap of Best Drugstore Serum

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